Advancing Small-Molecule Science from Discovery to Manufacture

API Development & Manufacturing

Science-Driven API Development, Built for Scale and Compliance

Aurapha is a research-driven pharmaceutical company specializing in the development, scale-up, and manufacturing of active pharmaceutical ingredients (APIs). Built on strong scientific foundations, we translate validated molecules into reliable, high-quality drug substances for global pharmaceutical markets.

Pipeline Products

Advancing Scientifically Validated Molecules Toward Reliable Supply

High-quality pharmaceutical product developed with an emphasis on process reliability, consistent quality, and scalable manufacturing, supporting research, formulation, and commercial pharmaceutical applications.

Urolithin A

Urolithin A is a postbiotic small molecule derived from ellagitannin metabolism and is a key regulator of mitochondrial quality control through mitophagy induction.

Resveratrol

Resveratrol is a well-studied polyphenolic compound with extensive scientific literature supporting its biological relevance.

Methylated Resveratrol derivative (DMU-212)

DMU-212 is a rationally designed, methylated analogue of resveratrol developed to enhance metabolic stability, bioavailability, and anticancer activity.

Pentadecanoic Acid (C15:0)

Pentadecanoic acid is an odd-chain saturated fatty acid increasingly recognized as a biomarker of metabolic and cardiometabolic health.

Peribedil

Peribedil is a dopaminergic agent with D₂/D₃ receptor agonist activity and additional vasodilatory properties, used clinically in Parkinson’s disease and vascular cognitive disorders.

Meclizine

Meclizine is a first-generation H₁ antihistamine with a long history of safe and effective use in the treatment of motion sickness and vertigo.

Buclizine

Buclizine is an established antihistamine with additional pharmacological effects relevant to appetite and metabolic regulation.

Flunarizine

Flunarizine is a calcium channel modulator with antihistaminic properties, widely used in migraine prevention and other chronic neurological conditions.

Cinnarizine

Cinnarizine is a well-established agent for the management of vertigo, motion sickness, and vestibular dysfunction, combining antihistaminic and calcium channel-blocking activity.

Our Focus Areas

Specialized Small-Molecule & Process Expertise

Aurapha’s research and development efforts are focused on scientifically validated small molecules and scalable chemical processes that support reliable API development and manufacturing for global pharmaceutical markets.

Small-Molecule Therapeutics

Postbiotics & Polyphenol Derivatives

Neurology & Metabolic Health Compounds

Process Chemistry & Scale-Up

Our Core Strengths

Scientific Excellence Driving Reliable API Development

Chemistry-Driven API Development

We bring deep expertise in synthetic organic chemistry and process development to design robust, scalable routes for complex small-molecule APIs.

Integrated Development & Manufacturing

Our integrated approach ensures seamless transition from laboratory development to pilot and commercial-scale manufacturing, minimizing risk and timelines.

Process Robustness & Reproducibility

We prioritize reproducible, well-controlled processes that deliver consistent quality across batches and scales.

Impurity & Quality Control Expertise

Early-stage impurity identification and control are embedded into our workflows to meet global regulatory and pharmacopeial standards.

Regulatory-Ready Mindset

Processes and documentation are developed with GMP, ICH, and global regulatory expectations in mind from the outset.

Experienced Multidisciplinary Team

Our team of highly qualified chemists and biologists brings strong scientific insight and practical manufacturing experience.

How We Work

Integrated. Scalable. Regulatory-Ready.

Our integrated development and manufacturing model ensures consistency, quality, and efficiency from early route design through commercial-scale production. We work closely with our partners to translate laboratory science into robust, manufacturable API processes.

Synthetic Route Development

We design and evaluate efficient synthetic routes at laboratory scale, focusing on feasibility, selectivity, and long-term manufacturability.

Process Optimization & Scale-Up

We optimize reaction conditions, reduce step count, and translate processes from gram to kilogram scale with safety, yield, and cost efficiency in mind.

Impurity Control & Analytical Characterization

We embed early-stage impurity identification and comprehensive analytical characterization to ensure consistent quality and regulatory alignment.

Solvent Recovery & Sustainability

Implementation of solvent selection, recovery, and recycling strategies to reduce environmental impact, waste generation, and overall process footprint.

GMP-Aligned Manufacturing Support

Development of processes and documentation aligned with GMP and ICH expectations, enabling smooth technology transfer and regulatory-ready manufacturing.